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Table 4 Univariate and multivariate analysis for DFS

From: Results of the observational prospective RealFLOT study

 

UNIVARIATE

MULTIVARIATE

Variable

HR with 95% CI

p value

HR with 95% CI

p value

Pathological stage

 1

1.3 (0.12–14)

0.8500

0.48 (0.02–8.74)

0.616

 2

7 (0.95–52)

0.0560

5.79 (0.43–78.08)

0.185

 3

14 (1.9–100)

0.0093

30.36 (1.75–526)

0.019

 4

30 (3.8–230)

0.0013

ypT1

2.6 (0.63–11)

0.1800

4.8 (0.72–32.05)

0.104

ypT2

3.6 (1.1–12)

0.0410

1.76 (0.36–8.68)

0.487

ypT3

5.6 (1.7–18)

0.0043

0.95 (0.20–4.37)

0.943

ypT4

4.7 (1.2–18)

0.0250

0.79 (0.15–4.19)

0.784

ypN1

1.9 (0.85–4.4)

0.1100

0.68 (0.23–2.03)

0.487

ypN2

3.3 (1.5–7.3)

3.2e-03

0.55 (0.16–1.89)

0.343

ypN3

4.8 (2.3–10)

4.6e-05

0.39 (0.09–1-54)

0.178

IntraOP MTS

3.9 (2–7.8)

7.6e-05

56.8 (3.5–906)

0.004

Postoperative CT

0.33 (0.2–0.54)

9.3e-06

0.32 (0.19–0.54)

2.3 e-05

  1. Abbreviations: CT chemotherapy; IntraOP MTS intraoperative metastasis; ypN postoperative N stage after preoperative chemotherapy; ypT postoperative T stage after preoperative chemotherapy