Fig. 5

The risk of top-ten combination cancers. The combination cases of the top-ten first primary cancers and subsequent second primary cancers for metachronous and synchronous multiple primary cancers (*, P < 0.0001; **, P < 0.01; 95% CI, 95% confidence interval; RR, relative risk of having multiple primary cancer versus having single primary cancer, adjusted for age at first primary cancer)