Demographic characteristics | HGIN/ESCC | LGIN | Esophagitis | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
OR (95% CI) | P value | Adjusted OR a (95% CI) | P value | OR (95% CI) | P value | Adjusted OR a (95% CI) | P value | OR (95% CI) | P value | Adjusted OR a (95% CI) | P value | |
Gender (Female) | 0.54 (0.45–0.66) | < 0.001 | – | – | 0.74 (0.68–0.82) | < 0.001 | – | – | 0.80 (0.76–0.85) | < 0.001 | – | – |
Age, years | ||||||||||||
 40–49 | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – |
 50–59 | 4.96 (3.12–8.40) | < 0.001 | – | – | 3.17 (2.65–3.81) | < 0.001 | – | – | 1.80 (1.65–1.96) | < 0.001 | – | – |
 60–69 | 15.73 (10.06–26.29) | < 0.001 | – | – | 7.18 (6.04–8.60) | < 0.001 | – | – | 2.84 (2.60–3.10) | < 0.001 | – | – |
Education (Formal) | 0.73 (0.58–0.94) | 0.013 | – | – | 0.68 (0.61–0.77) | < 0.001 | – | – | 0.93 (0.86–1.01) | 0.097 | – | – |
Annual income per family (RMB) | ||||||||||||
 < 10,000 | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – |
 10,000- | 0.65 (0.49–0.89) | 0.005 | – | – | 1.00 (0.86–1.18) | 0.973 | – | – | 0.86 (0.78–0.95) | 0.005 | – | – |
 30,000- | 0.80 (0.61–1.07) | 0.124 | – | – | 1.03 (0.88–1.20) | 0.725 | – | – | 1.02 (0.93–1.13) | 0.564 | – | – |
50,000- | 0.60 (0.43–0.85) | 0.004 | – | – | 0.82 (0.69–0.99) | 0.033 | – | – | 0.87 (0.78–0.98) | 0.018 | – | – |
≥70,000 | 0.42 (0.26–0.65) | < 0.001 | – | – | 0.58 (0.46–0.73) | < 0.001 | – | – | 0.90 (0.79–1.02) | 0.106 | – | – |
BMI | ||||||||||||
 18.5 to 23.9 | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – | 1.00 (reference) | – | – | – |
 < 18.5 | 1.69 (0.97–2.73) | 0.044 | – | – | 0.95 (0.67–1.32) | 0.791 | – | – | 1.02 (0.82–1.26) | 0.878 | – | – |
 24.0 to 27.9 | 0.80 (0.65–0.98) | 0.029 | – | – | 0.93 (0.84–1.03) | 0.166 | – | – | 0.97 (0.91–1.04) | 0.379 | – | – |
 ≥ 28.0 | 0.55 (0.37–0.78) | 0.001 | – | – | 0.76 (0.64–0.89) | 0.001 | – | – | 0.78 (0.70–0.86) | < 0.001 | – | – |
Family history of cancer | 1.50 (1.23–1.82) | < 0.001 | 1.64 (1.34–2.00) | < 0.001 | 1.24 (1.12–1.37) | < 0.001 | 1.33 (1.20–1.47) | < 0.001 | 1.19 (1.11–1.27) | < 0.001 | 1.22 (1.14–1.30) | < 0.001 |
History of chronic hepatitis and cirrhosis | 1.96 (1.07–3.28) | 0.018 | 1.91 (1.03–3.22) | 0.025 | 1.36 (0.96–1.86) | 0.067 | 1.36 (0.96–1.87) | 0.070 | 3.05 (2.60–3.57) | < 0.001 | 2.96 (2.52–3.47) | < 0.001 |