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Table 1 Patient characteristics and clinical outcome (nā€‰=ā€‰313)

From: Evaluating the effect of Neoadjuvant chemotherapy for esophageal Cancer using the RECIST system with shorter-axis measurements: a retrospective multicenter study

Clinical, epidemiological, pathological, and surgical features

Value

Mean ageā€‰Ā±ā€‰SD, years

66.5ā€‰Ā±ā€‰7.3

Male sex, n (%)

272 (87)

Performance status, n (%)

ā€ƒ0

222 (71)

ā€ƒ1

88 (28)

ā€ƒ2

3 (1)

Tumor location, n (%)

ā€ƒCe

1 (0.3)

ā€ƒUt

42 (13)

ā€ƒMt

144 (46)

ā€ƒLt

98 (31)

ā€ƒAe

28 (9)

Histopathological type, n (%)

ā€ƒSquamous cell carcinoma

279 (89)

ā€ƒAdenocarcinoma

20 (6)

ā€ƒOthers

14 (4)

Pretreatment clinical stage, n (%)

ā€ƒIB

7 (2)

ā€ƒII

53 (17)

ā€ƒIII

218 (70)

ā€ƒIV

35 (11)

NAC regimen, n (%)

ā€ƒPlatinum-based

203 (65)

ā€ƒTaxane-based

110 (35)

RECIST (longest diameter), n (%)

ā€ƒPR

126 (40)

ā€ƒSD

174 (56)

ā€ƒPD

13 (4)

RECIST (shorter axis), n (%)

ā€ƒPR

145 (46)

ā€ƒSD

150 (48)

ā€ƒPD

18 (6)

Severe morbidity, n (%)

ā€ƒCDCā€‰ā‰„ā€‰IIIb

34 (11)

Pathological stage, n (%)

ā€ƒ0ā€“I

60 (19)

ā€ƒII

88 (28)

ā€ƒIII

158 (41)

ā€ƒIV

37 (12)

TRG

ā€ƒ0

16 (5)

ā€ƒ1a

184 (59)

ā€ƒ1b

49 (16)

ā€ƒ2

45 (14)

ā€ƒ3

19 (6)

  1. Abbreviations: Ae abdominal esophagus, CDC Clavienā€“Dindo classification, Ce cervical esophagus, Lt lower thoracic, Mt mid-thoracic, NAC neoadjuvant chemotherapy, PD progressive disease, PR partial response, RECIST Response Evaluation Criteria in Solid Tumors, SD stable disease, SD standard deviation, TRG tumor regression grade, Ut upper thoracic