Table 2 Summary of the four cases of RAS-mutant glioma
From: Infrequent RAS mutation is not associated with specific histological phenotype in gliomas
| Â | Age | Sex | Location | Diagnosis | RAS mutation | Other genetic profile | PFS (months) | OS (months) |
|---|---|---|---|---|---|---|---|---|
Case 1 | 31 | F | frontal | AO-IDH mut + 1p/19qcodel | KRAS G12A | IDH1 R132H, TERT C250T, 1p/19q codeletion | 45 | 69+ |
Case 2 | 54 | F | frontal, genu of corpus callosum | AA-IDH wild type | KRAS E76D | MGMT promoter hyper methylation | 29 | 49 |
Case 3 | 45 | M | frontal, parietal | AA-IDH wild type | NRAS Q61R | Â | 3 | 24 |
Case 4 | 36 | M | occipital | Ganglioglioma | KRAS Q61K | Â | 18 | 32+ |