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Table 1 Number of mutations in each type of glioma

From: Infrequent RAS mutation is not associated with specific histological phenotype in gliomas

  Number of cases Driver gene mutations 1p/19q
codeleted
MGMTp
hypermethyl
RAS mutations
IDH1 IDH2 H3F3A HIST1H3B TERTp KRAS HRAS NRAS
DA, IDH-mutant 20 20 0 0 0 1 0 13 0 0 0
DA, IDH-wild type 18 0 0 0 0 8 0 7 0 0 0
AA, IDH-mutant 11 10 1 0 0 0 0 5 0 0 0
AA, IDH-wild type 32 0 0 0 0 15 0 10 1 0 1
GBM, IDH-mutant 4 4 0 0 0 0 0 2 0 0 0
GBM, IDH-wildtype 94 0 0 0 0 39 0 31 0 0 0
gliosarcoma 1 0 0 0 0 0 0 0 0 0 0
OD, IDH-mutant and 1p/19q codeleted 22 18 4 0 0 20 22 20 0 0 0
OD, NOS 4 2 1 0 0 3 0 2 0 0 0
AO, IDH mutant and 1p/19q codeleted 15 12 3 0 0 15 15 12 1 0 0
diffuse midline glioma, H3K27M mutant 9 0 0 8 1 1 0 1 0 0 0
ganglioglioma 1 0 0 0 0 0 0 0 1 0 0
PA 7 0 0 0 0 0 0 1 0 0 0
PMA 1 0 0 0 0 0 0 0 0 0 0
PXA 2 0 0 0 0 0 0 0 0 0 0
APXA 1 0 0 0 0 0 0 0 0 0 0
Total 242 66 9 8 1 102 37 104 3 0 1
  1. DA Diffuse astrocytoma, AA Anaplastic astrocytoma, GBM Glioblastoma, OD Oligodendroglioma, AO Anaplastic oligodendroglioma, PA Pilocytic astrocytoma, PMA Pilomyxoid astrocytoma, PXA Pleomorphic xanthoastrocytoma, APXA Anaplastic pleomorphic xanthoastrocytoma, TERTp TERT promoter, MGMTp MGMT promoter