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Fig. 4 | BMC Cancer

Fig. 4

From: A CTLA-4 blocking strategy based on Nanobody in dendritic cell-stimulated cytokine-induced killer cells enhances their anti-tumor effects

Fig. 4

Nb36 increased the abundance of IFN-γ-secreting effector DC-CIK cells. A Nb36-treated DC-CIK cells produced higher levels of pro-inflammatory cytokines viz. TNF-α and IL-2, except IL-10. DC-CIK cells were incubated with tumor cells for 16 h, and the levels of pro-inflammatory factors in the supernatants were determined by ELISA. B ELISPOT analysis of the frequency of IFN-γ-secreted DC-CIK cells. n = 3, *** P < 0.001

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