Skip to main content

Table 3 Association between circulating miR-1290 expression and clinicopathologic characteristics in 50 colorectal cancer patients

From: Circulating MiR-1290 as a potential diagnostic and disease monitoring biomarker of human gastrointestinal tumors

Variable

Total (n = 50)

miR-1290 expression

p value

Low (n = 23)

High (n = 27)

Age (year)

64.00 ± 1.62

63.26 ± 2.46

64.63 ± 2.19

0.679

Sex

   

0.057

 Male

33

12

21

 

 Female

17

11

6

 

BMI (kg/m2)

23.83 (21.33–25.54)

24.24 (20.96–27.64)

23.36 (21.45–25.24)

0.483

Smoke

   

0.741

 Yes

23

10

13

 

 No

27

13

14

 

Alcohol

   

0.990

 Yes

13

6

7

 

 No

37

17

20

 

Hypertension

   

0.309

 Yes

19

7

12

 

 No

31

16

15

 

Diabetes

   

0.777

 Yes

5

2

3

 

 No

45

21

24

 

Location

   

0.555

 colon

24

10

14

 

 rectum

26

13

13

 

Tumor size (cm)

3.50 (3.00–3.05)

3.00 (2.30–4.00)

4.00 (3.00–5.00)

0.037*

Lymphatic invasion

   

0.019*

 Positive

22

6

16

 

 Negative

28

17

11

 

Venous invasion

   

0.019*

 Positive

22

6

16

 

 Negative

28

17

11

 

Distant metastasis

   

0.041*

 Positive

16

4

12

 

 Negative

34

19

15

 

Differentiation

   

0.025*

 Well

1

1

0

 

 Moderate

39

21

18

 

 Poor

10

1

9

 

TNM stage (AJCC)

   

0.047*

 I and II

25

15

10

 

 III and IV

25

8

17

 

CRP (mg/l)

   

0.918

 < 10

41

19

22

 

 ≥ 10

9

4

5

 

CEA (ng/ml)

   

0.022*

 < 5

33

19

14

 

 ≥ 5

17

4

13

 

CA199 (U/ml)

   

0.400

 < 37

41

20

21

 

 ≥ 37

9

3

6

 

CA125 (U/ml)

   

0.351

 < 35

49

23

26

 

 ≥ 35

1

0

1

 

CA242 (U/ml)

   

0.183

 < 20

48

23

25

 

 ≥ 20

2

0

2

 

CA211 (ng/ml)

   

0.650

 < 5

47

22

25

 

 ≥ 5

3

1

2

 
  1. * p < 0.05