Fig. 5
Different antigen specific T cell responses in diverse tumour characteristics. The magnitude of CTA / SALL4-specific T cell response was compared in patients according to their tumour volume (in terms of SALL4 and MAGE-A3, there were 29 subjects in each group; in terms of others, there were 25 subjects with tumour volume < 15 cm3) (A), tumour number (in terms of SALL4 and MAGE-A3, there were 34 subjects with solitary and 24 with multiple lesions; in terms of others, there were 28 subjects with solitary and 19 with multiple lesions) (B), and without or with VI/M (in terms of SALL4 and MAGE-A3, there were 43 subjects without and 15 with VI/M; in terms of others, there were 34 subjects without and 13 with VI/M) (C). The comparison of AFP-specific T cell response between patients with different tumour characteristics (there were 26 subjects in 0/A stage and 33 subjects in B/C stage; 29 subjects in each tumour volume group; 34 subjects with solitary and 24 with multiple tumour lesions; 43 subjects without and 15 with VI/M) was presented in (D). Data were expressed as mean ± SEM, each dot represents one patient, and values were compared by Mann-Whitney U-test