Demographic and prognostic factors of optic nerve astrocytoma: a retrospective study of surveillance, epidemiology, and end results (SEER)

Table 2 The Relationship between Age at Diagnosis and Clinical Characteristics in ONAs Patients

Variables	Age ≤ 18	Age>18	Correlation Coefficient	P Value
Sex			0.07	0.026
Female	425	95
Male	413	71
Race			0.057	0.075
White	704	129
Black	59	21
Asian	35	9
Other	19	3
Unknown	21	4
Year of diagnosis			−0.002	0.950
<2010	504	112
≥ 2010	334	54
Surgery performance			0.064	0.045
Surgery, NOS	127	42
No surgery	701	122
Unknown	10	2
Tumor size			−0.137	0.034
≤ 2	98	36
>2	87	19
Unknown	653	111
Tumor grade			0.146	<0.001
I	30	12
II	30	10
III	1	1
IV	5	16
Unknown	772	127
Diagnostic Confirmation			0.099	0.002
Radiography without microscopic confirm	588	86
Clinical diagnosis only	21	4
Positive histology	208	73
Positive laboratory test/marker study	1	0
Direct visualization without microscopic confirmation	6	0
Positive microscopic confirm	2	0
Unknown	12	3
Tumor Extension			−0.011	0.733
Distant site(s)/node(s) involved	30	1
Localized only	596	117
Regional, NOS	76	13
Unknown	136	35
Laterality			−0.157	<0.001
Right - origin of primary	214	65
Left - origin of primary	205	39
Bilateral, single primary/paired site	221	23
Unknown	198	39
Histology Type			0.168	<0.001
Low-grade astrocytic tumors	810	143
High-grade astrocytic tumors	1	10
Astrocytoma, NOS	27	13

ISSN: 1471-2407