Cardiovascular disease in women with breast cancer – a nationwide cohort study

BMC Cancer

Table 4 Hazard ratio (HR) of different types of CVD in BC patients after chemotherapy

	Hypertension	Cerebrovascular disease	Ischemic heart disease/ACS^a	Atrial fibrillation	Heart failure	Thrombophlebitis/thrombosis	Pulmonary heart disease	Peripheral vascular disease	Heart valve disease	Other cardiac arrhythmias
Chemotherapy	0.849	1.012	1.004	1.189	1.738**	1.737**	1.408	0.962	1.014	1.130
Number of observations, N	15,574	16,000	15,874	16,080	16,245	16,387	16,453	16,411	16,388	16,396

The following covariates were included in the model: Age, region of residence, education, cohort (year of diagnosis), distant metastasis when diagnosed with BC and comorbidity at index date (CCI, diabetes or CVD (CVD at index date was defined by CVD drug prescriptions in NPDR
^* p < 0.05, ^** p < 0.01, ^*** p < 0.001
^aACS = Acute Cornoary Syndrome

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