Fig. 4

Exosomes played an important role in chemosensitivity of NPC cells. A: Representative images of exosomes from serum of NPC patients (serum-exo) or conditioned media of NPC cells (CM-exo) under Transmission electron microscopy (TEM). B: Nanoparticle tracking analysis was used to access the diameter of exosomes. C: Western blot was used to detect exosomal markers. Flotillin-1 was used as a loading control. D: Uptaken of exosomes by CNE2 cells was observed under confocal microscopy. Blue: Hoechst staining; green: PKH67-labeled exosomes. E: CCK8 was used to detect cell proliferation with the addition of NPC-derived exosomes. F: CCK8 was used to detect cell proliferation with cisplatin treatment after the addition of NPC-exosomes. *P < 0.05