From: Immediate risk of non-cancer deaths after a cancer diagnosis
Characteristics | Within 1 years since diagnosis | More than 1 year since diagnosis | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
No. of patients with cancer | Person-years of follow up | No. of observed deaths | No. of expected deaths | SMRa (95% CI) | No. of patients with cancer | Person-years of follow up | No. of observed deaths | No. of expected deaths | SMRa (95% CI) | |
All | 7,366,229 (100%) | 5,624,828 | 241,575 (100.0%) | 103,105.6 | 2.34 (2.33–2.35) | 5,425,172 (100%) | 36,196,870 | 864,975 (100.0%) | 478,513.4 | 1.81 (1.80–1.81) |
Age, y | ||||||||||
 0–19 | 92,844 (1.3%) | 78,747 | 583 (0.2%) | 54.7 | 10.66 (9.83–11.57) | 79,811 (1.5%) | 669,075 | 1080 (0.1%) | 502.5 | 2.15 (2.03–2.28) |
 20–39 | 442,398 (6.0%) | 372,394 | 7364 (3.0%) | 370.4 | 19.88 (19.43–20.34) | 377,627 (7.0%) | 3,211,248 | 11,940 (1.4%) | 3160.8 | 3.78 (3.71–3.85) |
 40–59 | 2,234,414 (30.3%) | 1,819,643 | 32,028 (13.3%) | 6296.1 | 5.09 (5.03–5.14) | 1,806,936 (33.3%) | 13,661,030 | 97,263 (11.2%) | 45,017.2 | 2.16 (2.15–2.17) |
 60–79 | 3,585,461 (48.7%) | 2,719,691 | 111,548 (46.2%) | 43,170.3 | 2.58 (2.57–2.60) | 2,606,293 (48.0%) | 16,492,660 | 514,259 (59.5%) | 260,950.5 | 1.97 (1.97–1.98) |
 80+ | 1,011,112 (13.7%) | 634,352 | 90,052 (37.3%) | 53,214.1 | 1.69 (1.68–1.70) | 554,505 (10.2%) | 2,162,857 | 240,433 (27.8%) | 168,882.4 | 1.42 (1.42–1.43) |
Sex | ||||||||||
 Female | 3,717,559 (50.5%) | 2,872,180 | 101,161 (41.9%) | 44,397.1 | 2.28 (2.26–2.29) | 2,794,614 (51.5%) | 19,176,433 | 377,760 (43.7%) | 194,247.3 | 1.94 (1.94–1.95) |
 Male | 3,648,670 (49.5%) | 2,752,647 | 140,414 (58.1%) | 58,708.5 | 2.39 (2.38–2.40) | 2,630,558 (48.5%) | 17,020,437 | 487,215 (56.3%) | 284,266.0 | 1.71 (1.71–1.72) |
Race | ||||||||||
 White | 6,068,860 (82.4%) | 4,653,123 | 194,848 (80.7%) | 88,602.2 | 2.20 (2.19–2.21) | 4,503,707 (83.0%) | 30,498,046 | 738,242 (85.3%) | 410,790.0 | 1.80 (1.79–1.80) |
 Black | 771,611 (10.5%) | 574,467 | 32,978 (13.7%) | 10,606.9 | 3.11 (3.08–3.14) | 542,333 (10.0%) | 3,238,518 | 85,172 (9.8%) | 50,241.0 | 1.70 (1.68–1.71) |
 AI/AN | 40,833 (0.6%) | 30,360 | 1310 (0.5%) | 342.7 | 3.82 (3.62–4.03) | 28,634 (0.5%) | 179,376 | 3894 (0.5%) | 1535.6 | 2.54 (2.46–2.62) |
 API | 484,925 (6.6%) | 366,878 | 12,439 (5.1%) | 3553.8 | 3.50 (3.44–3.56) | 350,498 (6.5%) | 2,280,930 | 37,667 (4.4%) | 15,946.8 | 2.36 (2.34–2.39) |
Year of diagnosis | ||||||||||
 1990–1999 | 1,319,905 (17.9%) | 1,019,773 | 55,329 (22.9%) | 22,522.2 | 2.46 (2.44–2.48) | 998,514 (18.4%) | 11,120,394 | 323,784 (37.4%) | 149,161.2 | 2.17 (2.16–2.18) |
 2000–2009 | 3,422,077 (46.5%) | 2,687,274 | 112,518 (46.6%) | 49,977.6 | 2.25 (2.24–2.26) | 2,675,604 (49.3%) | 20,562,263 | 457,002 (52.8%) | 268,827.0 | 1.70 (1.70–1.70) |
 2010–2016 | 2,624,247 (35.6%) | 1,917,780 | 73,728 (30.5%) | 30,605.8 | 2.41 (2.39–2.43) | 1,751,054 (32.3%) | 4,514,212 | 84,189 (9.7%) | 60,525.2 | 1.39 (1.38–1.40) |
Marital status | ||||||||||
 Married | 4,022,510 (54.6%) | 3,173,567 | 96,497 (39.9%) | 50,042.2 | 1.93 (1.92–1.94) | 3,107,029 (57.3%) | 21,986,915 | 441,489 (51.0%) | 266,531.8 | 1.66 (1.65–1.66) |
 Unmarried | 2,788,366 (37.9%) | 2,013,382 | 129,163 (53.5%) | 44,251.0 | 2.92 (2.90–2.93) | 1,881,706 (34.7%) | 11,414,836 | 352,443 (40.7%) | 169,938.6 | 2.07 (2.07–2.08) |
 Unknown | 555,353 (7.5%) | 437,878 | 15,915 (6.6%) | 8812.4 | 1.81 (1.78–1.83) | 436,437 (8.0%) | 2,795,119 | 71,043 (8.2%) | 42,042.9 | 1.69 (1.68–1.70) |
Stage | ||||||||||
 In situ | 451,459 (6.1%) | 405,558 | 4425 (1.8%) | 5442.4 | 0.81 (0.79–0.84) | 436,799 (8.1%) | 3,550,928 | 57,379 (6.6%) | 35,976.8 | 1.59 (1.58–1.61) |
 Localized | 2,838,911 (38.5%) | 2,505,010 | 57,978 (24.0%) | 45,487.3 | 1.27 (1.26–1.29) | 2,656,038 (49.0%) | 19,930,354 | 463,751 (53.6%) | 276,381.0 | 1.68 (1.67–1.68) |
 Regional | 1,189,160 (16.1%) | 961,350 | 40,351 (16.7%) | 16,393.8 | 2.46 (2.44–2.49) | 937,482 (17.3%) | 5,515,953 | 127,670 (14.8%) | 62,437.5 | 2.04 (2.03–2.06) |
 Distant | 1,294,149 (17.6%) | 732,298 | 56,706 (23.5%) | 13,720.3 | 4.13 (4.10–4.17) | 566,503 (10.4%) | 2,055,188 | 52,578 (6.1%) | 25,174.3 | 2.09 (2.07–2.11) |
 Unstaged | 1,592,550 (21.6%) | 1,020,611 | 82,115 (34.0%) | 22,061.8 | 3.72 (3.70–3.75) | 828,350 (15.3%) | 5,144,448 | 163,597 (18.9%) | 78,543.8 | 2.08 (2.07–2.09) |
Surgery | ||||||||||
 Yes | 4,373,773 (59.4%) | 3,717,285 | 79,762 (33.0%) | 57,493.4 | 1.39 (1.38–1.40) | 3,783,143 (69.7%) | 27,669,481 | 563,877 (65.2%) | 320,575.3 | 1.76 (1.75–1.76) |
 No | 2,926,045 (39.7%) | 1,862,953 | 159,261 (65.9%) | 44,599.3 | 3.57 (3.55–3.59) | 1,602,190 (29.5%) | 8,330,829 | 294,677 (34.1%) | 154,778.2 | 1.90 (1.90–1.91) |
 Unknown | 66,411 (0.9%) | 44,589 | 2552 (1.1%) | 1012.8 | 2.52 (2.42–2.62) | 39,839 (0.7%) | 196,560 | 6421 (0.7%) | 3159.9 | 2.03 (1.98–2.08) |
Chemotherapy | ||||||||||
 Yes | 1,947,887 (26.4%) | 1,511,435 | 40,799 (16.9%) | 16,992.5 | 2.40 (2.38–2.42) | 1,361,418 (25.1%) | 7,262,809 | 110,938 (12.8%) | 53,628.9 | 2.07 (2.06–2.08) |
 No/Unknown | 5,418,342 (73.6%) | 4,113,392 | 200,776 (83.1%) | 86,113.1 | 2.33 (2.32–2.34) | 4,063,754 (74.9%) | 28,934,062 | 754,037 (87.2%) | 424,884.5 | 1.77 (1.77–1.78) |
Radiotherapy | ||||||||||
 Yes | 2,021,621 (27.4%) | 1,635,770 | 32,758 (13.6%) | 22,878.1 | 1.43 (1.42–1.45) | 1,568,122 (28.9%) | 10,489,447 | 206,859 (23.9%) | 118,384.9 | 1.75 (1.74–1.75) |
 No/unknown | 5,344,608 (72.6%) | 3,989,058 | 208,817 (86.4%) | 80,227.5 | 2.60 (2.59–2.61) | 3,857,050 (71.1%) | 25,707,423 | 658,116 (76.1%) | 360,128.5 | 1.83 (1.82–1.83) |