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Table 2 Best overall response to treatment in the SOX+B-mab and SOX+C-mab population

From: Randomized phase II study of SOX+B-mab versus SOX+C-mab in patients with previously untreated recurrent advanced colorectal cancer with wild-type KRAS (MCSGO-1107 study)

Outcomes (RECIST v1.1)

SOX+B-mab

(n = 22)

SOX+C-mab

(n = 23)

Total

(n = 45)

Overall response rate (CR + PR)

13 (59.1%)

10 (43.5%)

23 (51.1%), P = 0.29

Disease control rate (CR + PR + SD)

20 (90.9%)

21 (91.3%)

41 (91.1%), P = 0.96

 Complete response (CR)

0 (0.0%)

0 (0.0%)

0 (0.0%)

 Partial response (PR)

13 (59.1%)

10 (43.5%)

23 (51.1%)

 Stable disease (SD)

7 (31.8%)

11 (47.8%)

18 (40.0%)

 Progressive disease (PD)

1 (4.5%)

1 (4.3%)

2 (4.4%)

 Could not be evaluated (NE)

1 (4.5%)

1 (4.3%)

2 (4.4%)

Conversion surgery

4 (18.2%)

3 (13.0%)

7 (15.6%)

 R0 resection

4 (18.2%)

1 (4.3%)

5 (11.1%), P = 0.19

 R2 resection

0

2 (8.7%)

2 (4.4%)