Brachytherapy with Iodine-125 seeds for treatment of portal vein-branch tumor thrombus in patients with hepatocellular carcinoma

Table 4 Univariate and multivariate analyses for OS

Risk Factor	Univariate			Multivariate
Risk Factor	HR	95% CI	p Value	HR	95% CI	p Value
Sex (F vs. M)	1.452	0.804–2.621	0.216
Age (≤60 y vs. > 60 y)	1.039	0.597–1.807	0.893
ECOG (0 + 1 vs. 2)	0.840	0.335–2.110	0.711
Child (A vs. B)	0.583	0.209–1.629	0.304
Treatment method (TACE-I-125 vs. TACE)	0.448	0.265–0.758	0.003**	0.482	0.276 ~ 0.841	0.010*
Type of PVTT (VP1 + VP2 vs. VP3)	0.421	0.247–0.719	0.002**	0.399	0.229 ~ 0.696	0.001*
Number of tumors (Single vs. Multiple)	0.800	0.479–1.338	0.352
Tumor Size (≤5 vs. > 5)	0.699	0.362–1.348	0.285
Extrahepatic metastasis (No vs Yes)	0.933	0.423–2.063	0.863
AFP (≤400 ng/mL vs. > 400 ng/mL)	0.606	0.344–1.066	0.082**	0.706	0.388 ~ 1.285	0.254

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