Bioinformatics analysis of the transcriptional expression of minichromosome maintenance proteins as potential indicators of survival in patients with cervical cancer

Table 1 Significant changes in MCM expression at the transcription level between cervical cancer tumor and normal tissues (ONCOMINE)

MCMs	Types	Fold Change	P-value	T-test	References
MCM2	CESC	5.984	2.3E-17	12.158	Scotto Cervix 2 [29]
	CESCE	5.714	3.12E-13	13.368	Zhai Cervix [30]
	CC	5.219	3.28E-14	11.233	Pyeon Multicancer [31]
	CESC	2.76	1.00E-05	11.995	Biewenga Cervix [32]
MCM3	CC	4.18	2.84E-13	11.188	Pyeon Multicancer [31]
	CESC	2.613	1.05E-10	7.947	Scotto Cervix 2 [29]
	CESCE	1.73	2.44E-07	7.464	Zhai Cervix [30]
	CESC	2.589	1.48E-06	12.088	Biewenga Cervix [32]
MCM4	CESCE	2.100	3.03E-11	10.279	Zhai Cervix [30]
	HG-CIN	2.161	0.001	3.672	Zhai Cervix [30]
	CC	4.103	1.48E-13	11.000	Pyeon Multicancer [31]
	CESC	3.175	3.90E-10	7.686	Scotto Cervix 2 [29]
	CESC	2.806	6.06E-06	12.289	Biewenga Cervix [32]
MCM5	CESC	4.399	3.80E-14	10.142	Scotto Cervix 2 [29]
	CC	3.623	3.49E-11	9.255	Pyeon Multicancer [31]
	CESCE	9.905	1.59E-05	7.196	Zhai Cervix [30]
	CESC	2.550	7.54E-06	13.686	Biewenga Cervix [32]
MCM6	CESC	3.731	6.25E-13	9.510	Scotto Cervix 2 [29]
	CC	4.004	3.28E-12	10.400	Pyeon Multicancer [31]
	CESCE	2.655	2.93E-07	8.894	Zhai Cervix [30]
	CESC	3.130	1.03E-07	17.000	Biewenga Cervix [32]
MCM7	CESC	3.728	5.77E-11	8.050	Scotto Cervix 2 [29]
	CESCE	3.233	5.10E-07	8.604	Zhai Cervix [30]
	HG-CIN	2.480	0.003	3.577	Zhai Cervix [30]
	CC	2.768	2.90E-09	7.790	Pyeon Multicancer [31]
	CESC	2.666	1.54E-07	13.539	Biewenga Cervix [32]
MCM8	CC	4.454	3.82E-14	11.480	Pyeon Multicancer [31]
	CESC	1.907	0.00000942	11.006	Biewenga Cervix [32]
MCM9					Need further study
MCM10	CESCE	2.287	0.00000367	5.779	Zhai Cervix [30]
	CESC	4.046	1.47E-06	5.463	Scotto Cervix 2 [29]
	CC	2.176	2.74E-08	7.154	Pyeon Multicancer [31]

Cervical squamous cell carcinoma epithelia: CESCE; High-grade cervical squamous intraepithelial neoplasia epithelia: HG-CIN; Cervical cancer: CC; Cervical squamous cell carcinoma: CESC

ISSN: 1471-2407