Fig. 1From: Downregulation of CCL22 and mutated NOTCH1 in tongue and mouth floor squamous cell carcinoma results in decreased Th2 cell recruitment and expression, predicting poor clinical outcomeData on infiltrating immune cells in samples derived from TCGA datasets. Th2 cell numbers were increased in early-stage T/MF SCC compared to advanced-stage T/MF SCC. (A) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using MCPcounter. (B) Relative number of T cells in early- and advanced-stage T/MF SCC samples calculated using MCPcounter. (C) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using ssGSEA and a gene signature from the literature [14]. This signature was termed as Immunity. (D) Relative numbers of Th2 cells in early- and advanced-stage T/MF SCC samples according to the Immunity signature. (E) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using ssGSEA and information on a gene signature obtained from the literature [13]. This signature was termed as 28 Immune cells. (F) Relative numbers of T cells in early- and advanced-stage T/MF SCC samples according to the 28 Immune cells signature. In heatmaps, red represents a high distribution, while blue represents a low distributionBack to article page