Skip to main content
Fig. 1 | BMC Cancer

Fig. 1

From: Downregulation of CCL22 and mutated NOTCH1 in tongue and mouth floor squamous cell carcinoma results in decreased Th2 cell recruitment and expression, predicting poor clinical outcome

Fig. 1

Data on infiltrating immune cells in samples derived from TCGA datasets. Th2 cell numbers were increased in early-stage T/MF SCC compared to advanced-stage T/MF SCC. (A) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using MCPcounter. (B) Relative number of T cells in early- and advanced-stage T/MF SCC samples calculated using MCPcounter. (C) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using ssGSEA and a gene signature from the literature [14]. This signature was termed as Immunity. (D) Relative numbers of Th2 cells in early- and advanced-stage T/MF SCC samples according to the Immunity signature. (E) Distribution of tumor-infiltrating immune cells in TCGA samples calculated using ssGSEA and information on a gene signature obtained from the literature [13]. This signature was termed as 28 Immune cells. (F) Relative numbers of T cells in early- and advanced-stage T/MF SCC samples according to the 28 Immune cells signature. In heatmaps, red represents a high distribution, while blue represents a low distribution

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us