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Table 7 Spearman’s correlation coefficient between the cellular factors with the HPV and EBV genes

From: Possible role of HPV/EBV coinfection in anoikis resistance and development in prostate cancer

 

LMP-1

LMP-2

EBER 1

EBER 2

E2

E6

E7

NF-κB

0.6****

0.43***

0.33**

0.31**

0.37**

0.64****

0.64****

TNF-α

0.49**

0.18 ns

0.19 ns

0.28*

0.271**

0.50***

0.504***

IL-1

0.501**

0.42**

0.34**

0.22*

0.40***

0.533***

0.529***

IL-6

0.66***

0.41**

0.11 ns

0.28*

0.309**

0.444***

0.435***

IL-8

0.54***

0.11 ns

0.07ns

0.08 ns

0.393**

0.603***

0.596***

IL-11

0.55***

0.3*

0.34*

0.136 ns

0.341***

0.504***

0.509***

IL-17

0.56***

0.41**

0.104 ns

0.09 ns

0.420***

0.726***

0.724***

VEGF

0.57****

0.39*

0.302*

0.07 ns

0.323**

0.595***

0.604***

TGF-β

0.51***

0.25*

0.103 ns

−0.08 ns

0.31**

0.55***

0.59****

Rb

−0.47***

0.39**

0.28**

0.22*

−0.553***

−0.751***

−0.751***

P53

−0.51***

−0.401*

−0.201*

−0.05 ns

−0.456***

−0.712***

−0.715***

Survivin

0.76****

0.39**

0.308**

0.17 ns

0.528***

0.757***

0.761***

Bcl-2

0.49***

0.39**

0.102 ns

−0.03 ns

0.556***

0.743***

0.743***

ROS

0.46**

0.29*

0.09 ns

0.105 ns

0.525***

0.763***

0.763***

RNS

0.301*

0.08 ns

0.02 ns

0.106 ns

0.460***

0.654***

0.652***

CD44

0.8****

0.68****

0.48***

0.58****

0.21*

0.34**

0.29**

TWIST

0.53****

0.44***

0.44***

0.045 ns

0/53**

0/83****

0/86****

E-cad

−0.5***

−0.2*

− 0.11*

− 0.096 ns

− 0/47**

− 0/71***

−0/71***

N-cad

0.51****

0.41**

0.42**

0.206 *

0/51**

0/85****

0/87****

PTPN13

−0.409***

− 0.15 ns

−0.15 ns

− 0.01 ns

− 0/48**

−0/41*

− 0/38*

SLUG

0.35*

0.05 ns

0.05 ns

0.10 ns

0/35*

0/46**

0/46**

  1. ns: not significant, * p < 0.05; ** p < 0.01; *** p < 0.001, **** < 0.0001