Table 4 Relationship between clinicopathologic parameters and the expression of TNFRSF14 in GC
From: Interaction between DNMT3B and MYH11 via hypermethylation regulates gastric cancer progression
Parameters | Total cases | TNFRSF14 mRNA expression | p value | TNFRSF14 IHC score | p value | |||
|---|---|---|---|---|---|---|---|---|
(n = 40) | High (n = 20) | Low (n = 20) | High (n = 20) | Low (n = 20) | ||||
Sex | Male | 26 | 16 | 10 | 0.0958 | 13 | 13 | >  0.9999 |
Female | 14 | 4 | 10 | 7 | 7 | |||
Age | ≧60 | 21 | 8 | 13 | 0.2049 | 9 | 12 | 0.5273 |
(year) | <  60 | 19 | 12 | 7 | 11 | 8 | ||
Tumor size | ≧3 | 25 | 17 | 8 | **0.0079 | 16 | 9 | *0.0484 |
(cm) | <  3 | 15 | 3 | 12 | 4 | 11 | ||
TNM stage | I + II | 17 | 3 | 14 | **0.0011 | 2 | 15 | ***0.0004 |
III + IV | 23 | 17 | 6 | 18 | 5 | |||
Tumor site | Upper GC | 22 | 11 | 11 | >  0.9999 | 14 | 8 | 0.1110 |
Distal end GC | 18 | 9 | 9 | 6 | 12 | |||
Lymph node metastasis | Positive | 25 | 17 | 8 | **0.0079 | 19 | 6 | ***0.0002 |
Negative | 15 | 3 | 12 | 1 | 14 | |||