Table 3 Relationship between clinicopathologic parameters and the expression of MYH11 in GC
From: Interaction between DNMT3B and MYH11 via hypermethylation regulates gastric cancer progression
Parameters | Total cases | MYH11 mRNA expression | p value | MYH11 IHC score | p value | |||
|---|---|---|---|---|---|---|---|---|
(n = 40) | High (n = 20) | Low (n = 20) | High (n = 20) | Low (n = 20) | ||||
Sex | Male | 26 | 12 | 14 | 0.7411 | 11 | 15 | 0.3203 |
Female | 14 | 8 | 6 | 9 | 5 | |||
Age | ≧ 60 | 21 | 12 | 9 | 0.5273 | 13 | 8 | 0.2049 |
(year) | <  60 | 19 | 8 | 11 | 7 | 12 | ||
Tumor size | ≧ 3 | 25 | 9 | 16 | *0.0484 | 7 | 18 | ***0.0008 |
(cm) | <  3 | 15 | 11 | 4 | 13 | 2 | ||
TNM stage | I + II | 17 | 13 | 4 | **0.0095 | 14 | 3 | **0.0011 |
III + IV | 23 | 7 | 16 | 6 | 17 | |||
Tumor site | Upper GC | 22 | 13 | 9 | 0.3406 | 10 | 12 | 0.7512 |
Distal end GC | 18 | 7 | 11 | 10 | 8 | |||
Lymph node metastasis | Positive | 25 | 9 | 16 | *0.0484 | 7 | 18 | ***0.0008 |
Negative | 15 | 11 | 4 | 13 | 2 | |||