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Table 3 Multivariable logistic analysis for predictors of STAS

From: Histopathologic features from preoperative biopsies to predict spread through air spaces in early-stage lung adenocarcinoma: a retrospective study

Variable

Odds Ratio(95% CI)

P Value

Histologic subtypes

1.35 (1.06–1.67)

0.016

Necrosis/Tumor Debris

1.03 (0.78–1.24)

0.131

ITB

1.64 (1.09–2.83)

0.011

Desmoplasia

1.83 (1.36–3.12)

< 0.001

Grade 3 Nuclei

1.00 (0.41–1.03)

0.464

N stage

1

 

1.37 (1.19–1.87)

0.013

1.29 (1.07–1.73)

0.039

  1. CI, confidence intervals; ITB, intratumoral budding; LVI, lymphovascular invasion