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Table 3 Multivariable logistic analysis for predictors of STAS

From: Histopathologic features from preoperative biopsies to predict spread through air spaces in early-stage lung adenocarcinoma: a retrospective study

Variable Odds Ratio(95% CI) P Value
Histologic subtypes 1.35 (1.06–1.67) 0.016
Necrosis/Tumor Debris 1.03 (0.78–1.24) 0.131
ITB 1.64 (1.09–2.83) 0.011
Desmoplasia 1.83 (1.36–3.12) < 0.001
Grade 3 Nuclei 1.00 (0.41–1.03) 0.464
N stage 1  
1.37 (1.19–1.87) 0.013
1.29 (1.07–1.73) 0.039
  1. CI, confidence intervals; ITB, intratumoral budding; LVI, lymphovascular invasion