Table 2 Association between spread through air spaces and pathologic variables of the biopsy specimens
variable | All patients | Negative for STAS (n = 75) | Positive for STAS (n = 36) | P value | |
|---|---|---|---|---|---|
Histologic subtypes | Others | 72 | 62 (82.7%) | 10 (27.8%) | < 0.001 |
Micropapillary/Solid | 39 | 13 (17.3%) | 26 (72.2%) | ||
Lymphovascular Invasion | Absent | 92 | 65 (86.7%) | 27 (75.0%) | 0.127 |
Present | 19 | 10 (13.3%) | 9 (25.0%) | ||
Chronic Inflammation | Absent | 57 | 38 (50.7%) | 19 (52.8%) | 0.835 |
Present | 54 | 37 (49.3%) | 17 (47.2%) | ||
Mucinous features | Mucin production | 12 | 7 (58.3%) | 5 (62.5%) | 0.859 |
Cytoplasmic mucin | 8 | 5 (41.7%) | 3 (37.5%) | ||
Necrotic/Tumor Debris | Absent | 69 | 64 (85.3%) | 5 (13.9%) | < 0.001 |
Present | 42 | 11 (14.7%) | 31 (86.1%) | ||
ITB | Absent | 78 | 62 (82.7%) | 16 (44.4%) | < 0.001 |
Present | 33 | 13 (17.3%) | 20 (55.6%) | ||
Desmoplasia | Absent | 70 | 69 (92.0%) | 1 (2.8%) | < 0.001 |
Present | 41 | 6 (8.0%) | 35 (97.2%) | ||
Grade 3 Nuclei | Absent | 97 | 73 (97.3%) | 24 (66.7%) | < 0.001 |
Present | 14 | 2 (2.7%) | 12 (33.3%) |