Fig. 3

Histological imaging in patients with tumor spread through air spaces (STAS) in PTNB specimens. (A) Photomicrograph image showing intratumoral budding in a lung adenocarcinoma with STAS. (B) Photomicrograph image showing desmoplasia in a lung adenocarcinoma with STAS. (C) Photomicrograph image showing grade 3 nuclei in a lung adenocarcinoma with STAS. (D) Photomicrograph image showing lymphovascular invasion in a lung adenocarcinoma with STAS. Note: For better reading, the brightness and contrast were modified in (B)