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Table 2 Top genes significantly correlated with PRRX1 in human HCC

From: Dysregulated paired related homeobox 1 impacts on hepatocellular carcinoma phenotypes

aGene symbol

Gene name

A1CF

APOBEC1 complementation factor

ACAA1

acetyl-CoA acyltransferase 1

ACOX2

acyl-CoA oxidase 2

ADH6

alcohol dehydrogenase 6 (class V)

CYB5A

cytochrome b5 type A

CYP2J2

cytochrome P450 family 2 subfamily J member 2

GGT5

gamma-glutamyltransferase 5

HNF1A

HNF1 homeobox A

IL10

interleukin 10

LIPC

lipase C, hepatic type

MGST2

microsomal glutathione S-transferase 2

MTTP

microsomal triglyceride transfer protein

NOX4

NADPH oxidase 4

PAH

phenylalanine hydroxylase

SLC2A2

solute carrier family 2 member 2

SLC7A8

solute carrier family 7 member 8

SORD

sorbitol dehydrogenase

ZEB1

zinc finger E-box binding homeobox 1

ZEB2

zinc finger E-box binding homeobox 2

  1. aThese genes significantly correlated with PRRX1 (P < 0.05) in two cohorts GSE14520 (n = 225 samples) and TCGA HCC (n = 371 samples). Pearson correlation analysis was used