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Fig. 3 | BMC Cancer

Fig. 3

From: Integrating HECW1 expression into the clinical indicators exhibits high accuracy in assessing the prognosis of patients with clear cell renal cell carcinoma

Fig. 3

Low HECW1 expression is predictive of unfavorable clinicopathological characteristics and poor postoperative prognosis in ccRCC patients. (a) A flow chart of the present study is shown. (b) Representative images of H&E and IHC staining of HECW1 in ccRCC specimens are presented (scale bar = 20 μm). The expression level of HECW1 in ccRCC was evaluated by the H-score method. (c) A time-dependent receiver operating characteristic (ROC) analysis was used to determine the optimum cut-off value of HECW1 in the randomized training cohort (at a 3:2 ratio). (d-g) Kaplan-Meier curves for the overall survival (OS) and progression-free survival (PFS) of ccRCC patients were analyzed according to HECW1 expression in the randomized training cohort (d, e) and validation cohort (f, g) (at a 3:2 ratio)

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