Fig. 5

Construction and validation of the thirteen-IRGs signature. A, LASSO coefficient profiles of the IRGs associated with the overall survival of CRC. B, Partial likelihood deviance for the LASSO coefficient profiles. C, The risk score distribution on the basis of the thirteen-IRGs signature in TCGA cohort. D, The survival status of 611 patients with CRC in high- and low-risk groups. E, Kaplan–Meier curves for overall survival prediction by the thirteen-IRGs signature in TCGA cohort. F, Time-dependent ROC curves for overall survival prediction by the thirteen-IRGs signature in TCGA cohort. G, The risk score distribution on the basis of the thirteen-IRGs signature in GSE39582 cohort. H, The survival status of 531 patients with CRC in high- and low-risk groups. I, Kaplan–Meier curves for overall survival prediction by the thirteen-IRGs signature in GSE3958 cohort. J, Time-dependent ROC curves for overall survival prediction by the thirteen-IRGs signature in GSE3958 cohort