Table 4 Comparison of Prediction Score and other indicators in predicting the progression of advanced NSCLC
Variables | Cutoff | AUC 95% CI | Sensitivity | Specificity | PPV | NPV | P |
|---|---|---|---|---|---|---|---|
Prediction Score | 16 | 0.825 (0.715,0.934) | 80.8% | 88.3% | 75.0% | 91.4% | < 0.0001 |
total MPs, events/μL | 2800 | 0.686 (0.559,0.813) | 69.2% | 68.3% | 48.6% | 83.7% | 0.006 |
NMPs, events/μL | 160 | 0.712 (0.598,0.827) | 69.2% | 65.0% | 46.2% | 83.0% | 0.002 |
PMPs, events/μL | 80 | 0.804 (0.706,0.903) | 84.6% | 68.3% | 53.7% | 91.1% | < 0.0001 |
NLR | 3.3 | 0.648 (0.513,0.784) | 57.7% | 78.3% | 53.6% | 81.0% | 0.029 |
CEA, ng/ml | 5.0 | 0.652 (0.515,0.788) | 69.2% | 65.0% | 46.2% | 83.0% | 0.026 |
CYFRA21-1, ng/ml | 2.5 | 0.741 (0.628,0.855) | 96.2% | 43.3% | 42.4% | 96.3% | 0.058 |
LDH, U/L | 210 | 0.694 (0.576,0.812) | 46.2% | 85.0% | 57.1% | 78.5% | 0.004 |