|
Variables
|
Cutoff
|
AUC 95% CI
|
Sensitivity
|
Specificity
|
PPV
|
NPV
|
P
|
|---|
|
Prediction Score
|
16
|
0.825 (0.715,0.934)
|
80.8%
|
88.3%
|
75.0%
|
91.4%
|
< 0.0001
|
|
total MPs, events/μL
|
2800
|
0.686 (0.559,0.813)
|
69.2%
|
68.3%
|
48.6%
|
83.7%
|
0.006
|
|
NMPs, events/μL
|
160
|
0.712 (0.598,0.827)
|
69.2%
|
65.0%
|
46.2%
|
83.0%
|
0.002
|
|
PMPs, events/μL
|
80
|
0.804 (0.706,0.903)
|
84.6%
|
68.3%
|
53.7%
|
91.1%
|
< 0.0001
|
|
NLR
|
3.3
|
0.648 (0.513,0.784)
|
57.7%
|
78.3%
|
53.6%
|
81.0%
|
0.029
|
|
CEA, ng/ml
|
5.0
|
0.652 (0.515,0.788)
|
69.2%
|
65.0%
|
46.2%
|
83.0%
|
0.026
|
|
CYFRA21-1, ng/ml
|
2.5
|
0.741 (0.628,0.855)
|
96.2%
|
43.3%
|
42.4%
|
96.3%
|
0.058
|
|
LDH, U/L
|
210
|
0.694 (0.576,0.812)
|
46.2%
|
85.0%
|
57.1%
|
78.5%
|
0.004
|
- PPV Positive predictive value, NPV Negative predictive value, MPs microparticals, NMPs neutrophil-derived microparticals, PMPs platelet-derived microparticles, CEA carcino-embryonic antigen, CYFRA-211 Cytokeratin 19 fragment, NLR neutrophil-lymphocyte ratio, LDH lactate dehydrogenase, CEA carcino-embryonic antigen
