Table 2 Univariate and multivariate analyses of the prognostic factors of OS in CRC patients from TCGA database
From: Upregulated NLGN1 predicts poor survival in colorectal cancer
Factors | Univariate analysis | Multivariate analysis | |||||||
|---|---|---|---|---|---|---|---|---|---|
Odd ratio | 95% CI | P value | Odd ratio | 95% CI | P value | ||||
Age | (per year) | 1.411 | 0.890 | 2.237 | 0.143 | ||||
Gender | (female vs. male) | 0.876 | 0.588 | 1.306 | 0.517 | ||||
Venus invasion | (yes vs. No) | 2.572 | 1.662 | 3.980 | 0.000 | 1.595 | 0.545 | 4.673 | 0.394 |
Perineural invasion | (yes vs. No) | 1.964 | 0.995 | 3.878 | 0.052 | 1.219 | 0.575 | 2.587 | 0.605 |
T stage | (T3–4 vs. T1–2) | 2.725 | 1.825 | 4.068 | 0.000 | 1.560 | 0.755 | 3.225 | 0.230 |
N stage | (N1–2 vs. N0) | 2.043 | 1.615 | 2.585 | 0.000 | 1.748 | 1.040 | 2.937 | 0.035 |
M stage | (M1 vs. M0) | 4.317 | 2.794 | 6.671 | 0.000 | 1.980 | 0.834 | 4.699 | 0.121 |
Tumor deposit | (yes vs. No) | 1.769 | 0.862 | 3.627 | 0.120 | ||||
Lymphatic invasion | (yes vs. No) | 2.146 | 1.397 | 3.296 | 0.000 | 0.685 | 0.218 | 2.156 | 0.518 |
NLGN1 expression | (high vs. low) | 2.219 | 1.482 | 3.323 | 0.000 | 2.524 | 1.254 | 5.083 | 0.010 |