Fig. 1

786–0 and RCC4 cell migration. A) Representative images of 786–0 WT and 786–0 WT + 1 μM PT2385 (PT) cells migrating 12 h after the scratch and wound confluence and wound width measure until the complete closure of the wound. n = 3. B) Representative images of RCC4 WT, RCC4 WT + 1 μM PT2385 (PT) and RCC4 VHL cells migrating 24 h after the scratch and wound confluence and wound width measure until the complete closure of the wound. n = 3. * represents comparison between RCC4 WT and RCC4 VHL and # represents comparison between RCC4 WT and RCC4 WT + 1 μM PT2385. Purple region corresponds to the initial scratch mask, whereas blue region represents the wound lacking cells at the compared moment. * p < 0.05, ** p < 0.01, *** p < 0.001. Errors bars depict standard error of the mean