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Table 2 Bivariate analyses of categorical variables associated with anxiety and depression

From: Clinical and genetic factors associated with anxiety and depression in breast cancer patients: a cross-sectional study

Variable

Anxiety (HADS-A total score)

Depression (HADS-D total score)

Education

 Primary

8.37 ± 6.07

7.69 ± 5.40

 Secondary

8.19 ± 5.36

6.87 ± 4.64

 University

10.12 ± 4.46

8.03 ± 4.15

p

0.131

0.415

Marital status

 Single/widowed/divorced

9.89 ± 4.99

8.83 ± 4.34

 Married

8.47 ± 5.30

6.98 ± 4.61

p

0.248

0.109

Dyslipidemia

 No

8.54 ± 5.31

7.09 ± 4.55

 Yes

9.30 ± 5.11

8.00 ± 4.78

p

0.502

0.427

Hypertension

 No

8.58 ± 5.00

7.07 ± 4.53

 Yes

9.00 ± 5.99

7.83 ± 4.82

p

0.885

0.437

Cyclophosphamide intake

 No

7.79 ± 5.08

7.30 ± 4.87

 Yes

9.51 ± 5.32

7.25 ± 4.38

p

0.07

0.974

Carboplatin intake

 No

9.01 ± 5.23

7.57 ± 4.61

 Yes

6.08 ± 4.89

4.83 ± 3.76

p

0.06

0.063

Fosaprepitant intake

 No

9.78 ± 5.51

8.03 ± 4.64

 Yes

6.46 ± 3.97

5.67 ± 4.15

p

0.002

0.014

CLOCK rs1801260

 TT

9.25 ± 5.38

7.25 ± 4.78

 TC

8.13 ± 5.14

7.02 ± 4.48

 CC

11.66 ± 2.51

9.33 ± 1.15

p

0.367

0.648

PER2 rs934945

 GG

8.72 ± 5.61

6.86 ± 4.95

 GA

8.56 ± 4.77

7.64 ± 3.85

 AA

7.75 ± 3.20

9.00 ± 4.69

p

0.982

0.329

CRY2 rs10838524

 GG

8.54 ± 4.53

6.88 ± 3.93

 AG

9.20 ± 5.56

7.50 ± 4.82

 AA

7.17 ± 5.93

7.23 ± 5.50

p

0.343

0.865

OPRM1 rs179971

 AA

8.96 ± 5.26

7.77 ± 4.60

 AG

7.35 ± 5.03

5.08 ± 3.87

p

0.170

0.014

ABCB1 rs1045642

 CC

9.05 ± 4.67

6.47 ± 3.96

 CT

8.17 ± 4.99

7.43 ± 5.11

 TT

8.68 ± 5.80

7.20 ± 4.41

p

0.760

0.789

COMT rs4680

 Val/Val

8.63 ± 5.09

6.94 ± 4.45

 Val/Met

7.84 ± 5.38

6.78 ± 4.33

 Met/Met

10.12 ± 5.08

8.54 ± 5.25

p

0.168

0.362

DRD2 rs6277

 CC

10.29 ± 4.83

8.11 ± 4.73

 CT

7.73 ± 4.84

6.63 ± 4.40

 TT

7.97 ± 5.38

6.50 ± 4.59

p

0.218

0.406

  1. Numbers in bold indicate significant p-values