Table 3 Data collection schedule
Follow-up | |||||||
|---|---|---|---|---|---|---|---|
Inclusion | Preop SRS | Surgery | M3 | M6 | M9 | M12 | |
Consent | ✓ | ||||||
Medical and surgical history | ✓ | ||||||
History of the disease | ✓ | ||||||
DS GPA classification | ✓ | ||||||
Serum Pregnancy Test (for woman of childbearing age) | ✓ | ||||||
Clinical examination | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
Previous and concomitant treatment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
Toxicity Evaluation (NCI CTCAE v5.0) | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | |
MMSE and EORTC QLQ-C30 questionnaires | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Surgery information (date, quality of surgery and post-operative follow-up) | ✓ | ||||||
Dosimetric brain MRI | ✓ | ||||||
Dosimetric CT scan | ✓ | ||||||
Tumor sample (FFPE block) | ✓ | ||||||
Dose delivered to target volumes and organs at risk | ✓ | ||||||
Paddick conformity Index and Gradient Index | ✓ | ||||||
Brain MRI | ✓a | ✓ | ✓ | ✓ | ✓ | ||