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Table 5 Mixed effects regression models

From: Cannabinoid exposure as a major driver of pediatric acute lymphoid Leukaemia rates across the USA: combined geospatial, multiple imputation and causal inference study

Parameter Estimates Model Parameters
Parameter Estimate (C.I.) P-Value S.D. AIC BIC logLik
ADDITIVE MODELS
lme (ALL_Rate ~ Cannabis)     
  Cannabis 0.33 (0.15, 0.51) 0.0004 0.4689 872.1647 889.0866 − 432.0824
Drugs
lme (ALL_Rate ~ Cigarettes + Cannabis + AUD + Analgesics + Cocaine)
  Cannabis 0.43 (0.23, 0.62) 2.7E-05 0.4668 863.5448 884.6873 − 426.7724
  Cocaine 10.44 (2.01, 18.87) 0.0156     
Drugs, Income & Ethnicity
lme (ALL_Rate ~ Cigarettes + Cannabis + AUD + Analgesics + Cocaine + Income + 5_Races)
  Hispanic 0.45 (0.33, 0.57) 2.7E-12 0.4478 813.8363 860.2190 −395.9182
  Cigarettes 5.21 (3.52, 6.9) 3.0E-09     
  Income 1 (0.56, 1.44) 1.2E-05     
  Cannabis 0.25 (0.06, 0.44) 0.0095     
  Analgesics −4.44 (−9.7, 0.82) 0.0986     
  Asian-American −0.14 (−0.29, 0.02) 0.0833     
  AIAN-American −4.72 (−8.06, −1.39) 0.0057     
  African-American −0.1 (− 0.17, − 0.03) 0.0056     
INTERACTIVE MODEL
lme (ALL_Rate ~ Cigarettes * Cannabis * AUD + Analgesics + Cocaine + Income + 5_Races)
  Hispanic 0.37 (0.28, 0.46) 7.0E-15 0.4508 809.6203 851.8063 −394.8101
  Cannabis: AUD 7.95 (4.69, 11.22) 2.5E-06     
  AUD 20.43 (11.44, 29.43) 1.1E-05     
  Income 0.85 (0.47, 1.23) 1.3E-05     
  AIAN-American −4.48 (−7.56, − 1.4) 0.0045     
  African-American −0.12 (−0.19, − 0.06) 0.0003     
  Cigarettes: Cannabis −1.83 (−2.52, − 1.15) 2.6E-07