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Table 4 Linear regression models

From: Cannabinoid exposure as a major driver of pediatric acute lymphoid Leukaemia rates across the USA: combined geospatial, multiple imputation and causal inference study

Parameter Parameter Model Parameters
Estimate (C.I.) P-Value SD R-Squared F dF P
lm (ALL_Rate ~ Cannabis)
 Cannabis 0.3 (0.18, 0.41) 4.3E-07 4.06E-01 0.4728 26.26 1508 4.2E-07
lm (ALL_Rate ~ Time)
 Year 0.01 (0, 0.01) 0.1670 4.06E-01 0.0018 1.916 1508 0.1670
lm (ALL_Rate ~ Time * Cannabis)
 Year 0.04 (−0.18, −0.02) 0.0130 0.4039 0.05638 11.14 3506 4.3E-07
 Cannabis 30.51 (13.22, 132.81) 0.0171      
 Year: Cannabis −0.02 (−0.07, − 0.01) 0.0176      
Additive model
lm (ALL_Rate ~ Cigarettes + AUD + Cannabis + Analgesics + Cocaine)
  cigmon −3.3 (− 4.19, −2.41) 1.3E-12 0.382 0.1561 32.38 3506 < 2.2E-16
  AUD 7.58 (5.17, 9.99) 1.5E-09      
  Cannabis 0.14 (0.03, 0.26) 0.0154      
Quintiles
lm (ALL_Rate ~ Quintile)
  Quintile 4 0.18 (0.07, 0.29) 0.0020 0.4071 0.0234 4.047 4505 0.0031
  Quintile 5 0.19 (0.06, 0.32) 0.0037      
lm (ALL_Rate ~ Year * Quintile)
  Year 0.03 (0.01, 0.05) 0.0061 0.4071 0.0416 3.456 9500 0.0004
  Quintile 3 79.2 (26.91, 131.49) 0.0031      
  Quintile 4 74.23 (21.02, 127.44) 0.0065      
  Quintile 5 61.55 (3.2, 119.9) 0.0392      
  Year: Quintile 3 −0.04 (− 0.07, − 0.01) 0.0032      
  Year: Quintile 4 − 0.04 (− 0.06, − 0.01) 0.0066      
  Year: Quintile 5 − 0.03 (− 0.06, 0) 0.0397      
lm (ALL_Rate ~ Year * Quintiles_Dichotomized)
  Upper Quintiles 0.15 (0.07, 0.22) 0.0001 0.4102 0.0272 15.24 1508 0.0001