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Table 13 e-Values

From: Cannabinoid exposure as a major driver of pediatric acute lymphoid Leukaemia rates across the USA: combined geospatial, multiple imputation and causal inference study

Parameter Estimate (C.I.) R.R. (C.I.) E-Values
Linear Models
lm (ALL_Rate ~ mrjmon)
  Cannabis 0.3 (0.18, 0.41) 1.94 (1.51, 2.51) 3.30, 2.38
lm (ALL_Rate ~ Time * mrjmon)
  Cannabis 30.51 (13.22, 132.81) 2.70E+ 71 (1.13E+ 13, 6.46E+ 129) 5.40E+ 71, 2.25E+ 13
Quintiles
lm (ALL_Rate ~ Quintile)
  Quintile 4 0.18 (0.07, 0.29) 1.49 (1.15, 1.91) 2.34, 1.59
  Quintile 5 0.19 (0.06, 0.32) 1.53 (1.15, 2.04) 2.43, 1.57
lm (ALL_Rate ~ Year * Quintile)
  Quintile 3 79.2 (26.91, 131.49) 7.55E+ 76 (1.67E+ 26, 3.41E+ 127) 1.51E+ 77, 3.34E+ 26
  Quintile 4 74.23 (21.02, 127.44) 1.13E+ 72 (3.23E+ 20, 3.96E+ 123) 2.26E+ 72, 6.50E+ 20
  Quintile 5 61.55 (3.2, 119.9) 5.54E+ 59 (1.65E+ 03, 1.85E+ 116) 1.11E+ 60, 3.31E+ 03
lm (ALL_Rate ~ Year * Dichotomized_Quintiles)
  Upper Quintiles 0.15 (0.07, 0.22) 1.99E+ 59 (1.56E+ 03, 2.54E+ 115) 3.99E+ 59, 3.13E+ 03
Legal Status
lm (Rate ~ Status)
  Legal 0.3 (0.12, 0.49) 1.98 (1.31, 2.98) 3.37, 1.95
  Medical 0.21 (0.12, 0.31) 1.62 (1.30, 2.00) 2.62, 1.94
lm (Rate ~ Year * Status)
  Legal 0.3 (0.12, 0.49) 1.98 (1.31, 2.98) 3.37, 1.95
  Medical 0.21 (0.12, 0.31) 1.62 (1.30, 2.00) 2.62, 1.94
lm (Rate ~ Year * Dichotomized Status)
  Liberal 0.11 (0.04, 0.18) 1.27 (1.08, 1.49) 1.85, 1.38
Additive model
lm (ALL_Rate ~ Cigarettes + AUD + Cannabis + Analgesics + Cocaine)
 Cannabis 0.14 (0.03, 0.26) 1.40 (1.06, 1.84) 2.16, 1.34
MIXED EFFECTS MODELS
ADDITIVE MODELS
lme (ALL_Rate ~ Cannabis)
  Cannabis 0.33 (0.15, 0.51) 1.30 (1.04, 2.47) 2.58, 1.24
Drugs
lme (Rate ~ Cigarettes + Cannabis + AUD + Analgesics + Cocaine)
  Cannabis 0.43 (0.23, 0.62) 2.29 (1.56, 3.37) 4.02, 2.50
Drugs, Income & Ethnicity
lme (ALL_Rate ~ Cigarettes + Cannabis + AUD + Analgesics + Cocaine + Income + 5_Races)
  Cannabis 0.25 (0.06, 0.44) 1.66 (1.14, 2.44) 2.72, 1.53
INTERACTIVE MODEL
lme (ALL_Rate ~ Cigarettes * Cannabis * AUD + Analgesics + Cocaine + Income + 5_Races)
  Cannabis: AUD 7.95 (4.69, 11.22) 9.40E+ 06 (1.29E+ 04, 6.81E+ 09) 1.88E+ 07, 2.59E+ 04
GEOSPATIAL MODELS
Cannabis Alone
spreml (ALL_Rate ~ Cannabis)
  Cannabis 0.22 (0.09, 0.36) 3.44 (1.61, 7.36) 6.34, 2.60
Additive Model
spreml (ALL_Rate ~ Cigarettes + Cannabis + AUD + Analgesics + Cocaine)
  Cannabis 0.16 (0.06, 0.27) 1.47 (1.14, 1.90) 2.31, 1.54
Interactive Models - Drugs
spreml (ALL_Rate ~ Cigarettes * Cannabis * AUD + Analgesics + Cocaine)
  Cigarettes: Cannabis: AUD 22.02 (10.13, 33.91) 1.38E+ 23 (4.65E+ 10, 4.11E+ 35) 2.77E+ 23, 9.30E+ 10
Interactive Cannabinoid Models - Drugs, Income, Ethnicity
spreml (ALL_Rate ~ Cigarettes * Cannabis * AUD + Analgesics + Cocaine + Income + 5_Races)
  Cannabigerol 0.26 (−3.68, 4.2) 2.04 (1.02, 4.11) 3.51, 1.16
ETHNICITY MODELS
Ethnic THC Exposure - Additive
spreml (ALL_Rate ~ Caucasian-Am._THC_Exp + African-Am._THC_Exp + Hispanic-Am._THC_Exp + Asian-AM._THC_Exp + AIAN-Am.THC_Exp + NHPI_THC_Exp)
  HispanicTHC_Expos. 0.39 (0.13, 0.65) 2.47 (1.34, 4.54) 4.37, 2.01
  NHAfrican-Am.THC_Expos. 0.34 (0.06, 0.63) 2.11 (1.09, 4.07) 3.65, 1.43
Ethnic THC Exposure - Interactive
spreml (ALL_Rate ~ Caucasian-Am._THC_Exp * African-Am._THC_Exp * Hispanic-Am._THC_Exp + Asian-AM._THC_Exp + AIAN-Am.THC_Exp + NHPI_THC_Exp)
  NHCaucas.-Am.THC_Expos.: NHAfrican-Am.THC_Expos.: HispanicTHC_Expos. 0.12 (0.04, 0.2) 1.33 (1.10, 1.59) 1.98, 1.43
spreml (ALL_Rate ~ Cigarettes * AUD + Analgesics + Cocaine + Caucasian-Am._THC_Exp * African-Am._THC_Exp * Hispanic-Am._THC_Exp + Asian-AM._THC_Exp + AIAN-Am.THC_Exp + NHPI_THC_Exp)
  NHCaucas.-Am.THC_Expos.: NHAfrican-Am.THC_Expos.: HispanicTHC_Expos. 0.12 (0.04, 0.2) 1.36 (1.12, 1.66) 2.06, 1.48
Ethnic Imputed Models
Additive Model
  Ethnic_THC_Exposure 0.53 (0.44, 0.61) 1.78 (1.62, 1.96) 2.97, 2.64
Interactive Model
  Ethnic_THC_Exposure 0.42 (0.35, 0.5) 1.59 (1.46, 1.72) 2.55, 2.29
Interactive Model with Cannabinoids
  Cannabigerol 2.14 (1.65, 2.63) 16.99 (8.90, 34.42) 33.47, 17.29
  Cigarettes: Ethic_THC_Exposure 3.77 (3.12, 4.42) 146.54 (62.25, 344.97) 292.59, 124.00
  AUD: Ethnic_THC_Exposure 6.98 (5.08, 8.88) 1.01E+ 04 (829.80, 1.24E+ 05) 2.03E+ 04, 1.66E+ 03
Interactive Model with Race & Income
  Ethic_THC_Exposure 0.64 (0.55, 0.72) 2.05 (1.85, 2.27) 3.52, 3.11
Interactive Model with Race & Income & Cannabis Intensity
  Cigarettes: Ethic_THC_Exposure 4.69 (3.77, 5.61) 279.13 (92.59, 841.47) 557.76, 184.68
Cannabis_Use_Intensity
  NH Caucasian-American 8.93 (6.2, 11.66) 1.66E+ 52 (1.97E+ 36, 1.39E+ 68) 3.32E+ 52, 32.94E+ 36