Table 3 Best response to CXD101 in patients dosed at CXD101 doses of ≥16 mg twice daily
Response | Solid organ, all HR23B positive N = 11 | Lymphoma HR23B Negative N = 7 | Lymphoma HR23B Positive N = 15 | Lymphoma HR23B score not available N = 1 | Lymphoma total N = 23 | All patients N = 34 |
|---|---|---|---|---|---|---|
NE | 2 | 1 | 0 | 0 | 3 | 5 |
PD | 5 | 2 | 7 | 1 | 8 | 13 |
SD | 4 | 2 | 6 | 0 | 8 | 12 |
PR | 0 | 2 | 1 | 0 | 3 | 3 |
CR | 0 | 0 | 1 | 0 | 1 | 1 |
ORR | 0 | 29% | 13% | 0% | 17% | 12% |