Table 2 Summary of differentially expressed genes between PTEN-null and PTEN-intact in the TCGA cohort. Number of differentially expressed genes with logFC greater than 1 and FDR lesser than 0.01 across different ERG backgrounds. The number in parenthesis shows the number of genes exclusive to the FANTOM-CAT annotations
From: Transcriptional landscape of PTEN loss in primary prostate cancer
| PTEN-null vs PTEN-intact overall | PTEN-null vs PTEN-intact in ERG-fusion | PTEN-null vs PTEN-intact in ERG-intact | |
|---|---|---|---|
| Coding genes | 257 (13) | 226 (7) | 185 (10) |
| Non-coding genes | 264 (134) | 209 (117) | 179 (82) |
| Total | 521 (137) | 435 (124) | 364 (92) |