Table 4 Adverse events
Grade 1 (%) | Grade 2 (%) | Grade 3 (%) | Grade 4 (%) | Grade 3 + 4% | |
|---|---|---|---|---|---|
Hematological | |||||
Anemia | 14 (29.8) | 19 (40.4) | 0 | 0 | 0.0 |
Neutropenia | 6 (12.8) | 18 (38.3) | 8 (17.0) | 1 (2.1) | 19.1 |
Lymphopenia | 3 (6.4) | 3 (6.4) | 28 (59.6) | 13 (27.7) | 87.3 |
Thrombopenia | 21 (44.7) | 9 (19.2) | 2 (4.3) | 2 (4.3) | 8.6 |
Non-hematological | |||||
Nausea | 7 (14.9) | 5 (10.6) | 2 (4.3) | 0 | 4.3 |
Vomiting | 4 (8.5) | 4 (8.5) | 1 (2.1) | 0 | 2.1 |
Anorexia | 16 (34.0) | 7 (14.9) | 4 (8.5) | 0 | 8.5 |
Constipation | 12 (25.5) | 26 (55.3) | 0 | 0 | 0.0 |
ALT elevation | 16 (34.0) | 10 (21.3) | 2 (4.3) | 0 | 4.3 |
Hyponatremia | 26 (55.3) | 3 (6.4) | 2 (4.3) | 0 | 4.3 |
Hyperpotassemia | 11 (23.4) | 1 (2.1) | 1 (2.1) | 0 | 2.1 |
Skin rush | 3 (6.4) | 4 (8.5) | 0 | 0 | 0.0 |
Fever | 15 (31.9) | 0 | 0 | 0 | 0.0 |
Febrile neutropenia | – | – | 0 | 0 | 0.0 |
Others | 3 (6.4) | 0 | 3 (6.4) | 0 | 6.4 |