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Fig. 1 | BMC Cancer

Fig. 1

From: TRAIL-coated leukocytes to kill circulating tumor cells in the flowing blood from prostate cancer patients

Fig. 1

Fluctuations in the CTC counts induced by primary tumor resection (a) Immunofluorescent staining of CTCs isolated from one PC patient at different time points (red is CD45, green is cytokeratin and blue is DAPI) showing the increase in CTC level through cancer treatment. Scale bar represents 20 μm. (b) Box and whisker plot represents the CTC count in samples from PC patients at different time points: diagnosis, surgery, 2 days post-surgery and 2 weeks post-surgery. (mean ± SD, n = 48 samples from 13 patients). A slight increase of CTC (P = 0.0698) over surgical tumor removal was determined using one-way ANOVA. (c) A stacked column chart shows the CTC counts in PC patients who developed cancer recurrence at different time points (n = 8 samples from 2 patients). Significant increase (**P = 0.0030) in the number of CTCs following surgical resection of primary tumor was calculated using the correlation test. (d) CTC counts in PC patients at 2 weeks post-surgery compared with the grade of PC (n = 14 samples from 14 patients)

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