Genetic polymorphisms and haplotypes of ERCC1 and ERCC2 associated with quality of life, depression, and anxiety status among patients with lung cancer

Table 2 Haplotypes of ERCC1, ERCC2 gene

Gene	SNPs	Haplotype	Quantity	Frequency*
ERCC1	rs762562-rs3212986	GC (ref)	243	0.4175
ERCC1	rs762562-rs3212986	AA	191	0.3282
ERCC1	rs762562-rs3212986	AC	147	0.2526
ERCC1	rs3212986-rs11615	CG (ref)	242	0.4158
ERCC1	rs3212986-rs11615	AG	191	0.3282
ERCC1	rs3212986-rs11615	CA	148	0.2543
ERCC2	rs13181-rs3916874-rs238416	TCT (ref)	266	0.4570
ERCC2	rs13181-rs3916874-rs238416	TCC	156	0.2680
ERCC2	rs13181-rs3916874-rs238416	TGC	111	0.1907
ERCC2	rs13181-rs3916874-rs238416	GCC	49	0.0842

Note: when calculating the frequency, the numerator = the corresponding number of haplotype, denominator = 2 * sample size. * means multiplication

ISSN: 1471-2407