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Fig. 8 | BMC Cancer

Fig. 8

From: The combined effect of dichloroacetate and 3-bromopyruvate on glucose metabolism in colorectal cancer cell line, HT-29; the mitochondrial pathway apoptosis

Fig. 8

Fig. 8: Flow cytometry assessment of apoptosis and necrosis in HT-29 cell line after 48 h treatment with 3Br-P, DCA, and 5-FU alone and/or combined together. Data presented as Mean ± SEM. *: (p<0.05) designates significant difference with control, #: (p<0.05) designates significant difference with control, 3 Br-P and DCA, $: (p<0.05) designates significant difference with control, 3Br-P, DCA, and/or combined together. Treated cells were stained with Annexin V-FITC/ PI assay. Four quadrants (Q) representing normal cells (Q4), early apoptosis cells (Q3), late apoptotic/necrotic cells (Q2) and necrotic cells (Q1)

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