Table 1 Patients‘demographic, clinical and histological characteristics. Patients were divided in two groups: vitamin D sufficient and insufficient using the baseline serum vitamin D level cut-off of 30 ng/mL (75 nmol/L)

 Age (years), median [range]

55

[20–68]

52.5

[35–71]

53

[20–71]

 Pre-menopausal

6

(37.5)

29

(44.6)

35

(43.2)

 Post-menopausal

10

(62.5)

36

(55.4)

46

(56.8)

 Missing

0

1

1

  0

16

(100)

59

(89.4)

75

(91.5)

  1

0

(0)

7

(10.6)

7

(8.5)

 Weight (kg), median [range]

62

[48–88]

64.5

[40–95]

64

[40–95]

 Height (cm), median [range]

164

[157–170]

161

[149–178]

162.5

[149–178]

 BSA (m²), median [range]

1.71

[1.46–1.93]

1.71

[1.32–2.06]

1.71

[1.32–2.06]

  < 25

10

(62.5)

36

(54.5)

46

(56.1)

  ≥ 25

6

(37.5)

30

(45.5)

36

(43.9)

  1

0

(0)

2

(3.0)

2

(2.5)

  2

8

(50)

39

(59.1)

47

(57.3)

  3

8

(50)

25

(37.9)

33

(40.2)

  No

10

(62.5)

48

(72.7)

58

(70.7)

  Yes

6

(37.5)

18

(27.3)

24

(29.3)

   < 10%

1

(6.2)

9

(13.6)

10

(12.2)

   ≥ 10%

15

(93.8)

57

(86.4)

72

(87.8)

   < 10%

3

(18.7)

18

(27.3)

21

(25.6)

   ≥ 10%

13

(81.3)

48

(72.7)

61

(74.4)

  No

14

(87.5)

57

(87.7)

71

(87.7)

  Yes

2

(12.5)

8

(12.3)

10

(12.3)

  Missing

0

1

1

  No

15

(93.8)

60

(90.9)

75

(91.5)

  Yes

1

(6.2)

6

(9.1)

7

(8.5)

  I

9

(56.3)

21

(32.8)

30

(37.5)

  IIA

5

(31.2)

21

(32.8)

26

(32.5)

  IIB

2

(12.5)

15

(23.4)

17

(21.3)

  IIIA

0

(0.0)

6

(9.4)

6

(7.5)

  IIIC

0

(0.0)

1

(1.6)

1

(1.2)

  Missing

0

2

2