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Fig. 3 | BMC Cancer

Fig. 3

From: TRIM27 interacts with Iκbα to promote the growth of human renal cancer cells through regulating the NF-κB pathway

Fig. 3

oeTRIM27 rescues the function of TRIM27 in siTRIM27-transfected cells. A and B. The proliferations of Caki-2 and 786–0 cells transfected with siTRIM27, oeTRIM27, or siTRIM27 + oeTRIM27 at 0, 12, 24, and 48 h respectively. *p < 0.05 vs Control, ***p < 0.001 vs Control. C and D. Flow cytometric evaluation of the apoptosis of Caki-2 and 786–0 cells transfected with siTRIM27, oeTRIM27, or siTRIM27 + oeTRIM27 at 48 h respectively, ***p < 0.001 vs Control. D and E. Western blot was used to examine the relative proteins of TRIM27, cleaved caspase-3, NF-κB (cytoplasm), and NF-κB (nuclear) in Caki-2 and 786–0 cells transfected with siTRIM27, oeTRIM27, or siTRIM27 + oeTRIM27 at 48 h respectively. ***p < 0.001 vs Control

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BMC Cancer

ISSN: 1471-2407

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