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Table 1 Clinicopathological characteristics before and after PSM

From: Impact of surgical margin width on long-term outcomes for intrahepatic cholangiocarcinoma: a multicenter study

 

Before PSM

After PSM

Wide

Narrow

P-Value

Wide

Narrow

P-Value

(n = 195)

(n = 283)

(n = 79)

(n = 79)

Gender

 Male

103 (52.8%)

184 (65.0%)

0.010

51 (64.6%)

47 (59.5%)

0.623

 Female

92 (47.2%)

99 (35.0%)

 

28 (35.4%)

32 (40.5%)

 

Age

  ≤ 60 years

115(59.0%)

177(62.5%)

0.489

42(53.2%)

50(63.3%)

0.259

  > 60 years

80(41.0%)

106(7.5%)

 

37(46.8%)

29(36.7%)

 

HBsAg

 Negative

144 (73.8%)

184 (65.0%)

0.052

55(69.6%)

59(74.7%)

0.594

 Positive

51 (26.2%)

99 (35.0%)

 

24(30.4%)

20(25.3%)

 

CA19–9

  ≤ 200 U/mL

136 (69.7%)

253 (89.4%)

< 0.001

63(79.7%)

65(82.3%)

0.839

  > 200 U/mL

59 (30.3%)

30 (10.6%)

 

16(20.3%)

14(17.7%)

 

CEA

  ≤ 5 μg/L

125 (64.1%)

234 (82.7%)

< 0.001

56(70.9%)

56(70.9%)

1.000

  > 5 μg/L

70 (35.9%)

49 (17.3%)

 

23(29.1%)

23(29.1%)

 

Blood loss

  ≤ 400 mL

141(72.3%)

229(80.9%)

0.036

61(77.2%)

57(72.2%)

0.583

 >400 mL

54(27.7%)

54(19.1%)

 

18(22.8%)

22(27.8%)

 

Transfusion

 No

148(75.9%)

246(86.9%)

0.003

60(75.9%)

61(77.2%)

1.000

 Yes

47(24.1%)

37(13.1%)

 

19(24.1%)

18(22.8%)

 

Laparoscopic approach

 No

163 (83.6%)

281 (99.3%)

< 0.001

76 (96.2%)

77 (97.5%)

1.000

 Yes

32 (16.4%)

2 (0.7%)

 

3 (3.8%)

2 (2.5%)

 

Major hepatectomy

 No

72 (36.9%)

80 (28.3%)

0.058

32(40.5%)

31(39.2%)

1.000

 Yes

123 (63.1%)

203(71.7%)

 

47(59.5%)

48(60.8%)

 

Complications

 No

137 (70.3%)

233 (82.3%)

0.003

60 (75.9%)

59 (74.7%)

1.000

 Yes

58 (29.7%)

50 (17.7%)

 

19 (24.1%)

20 (25.3%)

 

Tumor size

  ≤ 5 cm

86 (44.1%)

94 (33.2%)

0.020

37(46.8%)

34(43.0%)

0.749

  > 5 cm

109 (55.9%)

189 (66.8%)

 

42(53.2%)

45(57.0%)

 

Tumor number

 Single

163 (83.6%)

181 (64.0%)

< 0.001

61(77.2%)

60(75.9%)

1.000

 Multiple

32 (16.4%)

102 (36.0%)

 

18(22.8%)

19(24.1%)

 

Lymph node invasion

 No

140 (71.8%)

250 (88.3%)

< 0.001

67 (84.8%)

69 (87.3%)

0.818

 Yes

55 (28.2%)

33 (11.7%)

 

12 (15.2%)

10 (12.7%)

 

Mass-forming

 No

38 (19.5%)

116 (41.0%)

< 0.001

28(35.4%)

19(24.1%)

0.164

 Yes

157 (80.5%)

167 (59.0%)

 

51(64.6%)

60(75.9%)

 

Tumor differentiation

 Well &Moderate

139 (71.3%)

236 (83.4%)

0.002

64(81.0%)

60(75.9%)

0.561

 Poor

56 (28.7%)

47 (16.6%)

 

15(19.0%)

19(24.1%)

 

Satellite

 No

170 (87.2%)

181 (64.0%)

< 0.001

65(82.3%)

62(78.5%)

0.689

 Yes

25 (12.8%)

102 (36.0%)

 

14(17.7%)

17(21.5%)

 

MVI

 No

165 (84.6%)

254 (89.8%)

0.124

72(91.1%)

68(86.1%)

0.453

 Yes

30 (15.4%)

29 (10.2%)

 

7(8.9%)

11(13.9%)

 

Perineural invasion

 No

164 (84.1%)

261 (92.2%)

0.008

66(83.5%)

69(87.3%)

0.652

 Yes

31 (15.9%)

22 (7.8%)

 

13(16.5%)

10(12.7%)

 

p-AT

 No

141(72.3%)

240(84.8%)

0.001

64(81.0%)

66(83.5%)

0.835

 Yes

54(27.7%)

43(15.2%)

 

15(19.0%)

13(16.5%)

 
  1. Abbreviations: PSM propensity score matching, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9, HBsAg hepatitis B surface antigen, MVI microvascular invasion, p-AT postoperative adjuvant therapy