Table 1 Tumor and patient characteristics stratified by different groups
Characteristics | Total n = 3761 (%) | HER2-neg n = 3313 (%) | HER2-pos-T n = 448 (%) | P value |
|---|---|---|---|---|
Age (y/o) | 55 (46–64) | 56 (46–65) | 51 (44–59) | <  0.001 |
Menstrual status |  |  |  | <  0.001 |
Pre/Peri- | 1562 (41.5) | 1333 (40.2) | 229 (51.1) | Â |
Post- | 2199 (58.5) | 1980 (59.8) | 219 (48.9) | Â |
Histology type |  |  |  | <  0.001 |
IDC | 3085 (82.0) | 2679 (80.9) | 406 (90.6) | Â |
Non-IDC | 676 (18.0) | 634 (19.1) | 42 (9.4) | Â |
Histological grade |  |  |  | <  0.001 |
I/II | 2395 (63.7) | 164 (65.4) | 231 (51.6) | Â |
III | 796 (21.2) | 614 (18.5) | 182 (40.6) | Â |
NA | 570 (15.1) | 535 (16.1) | 38 (7.8) | Â |
Tumor size |  |  |  | <  0.001 |
≤ 2.0 cm | 2251 (59.5) | 2039 (61.5) | 212 (47.3) |  |
>  2.0 cm | 1510 (40.1) | 1274 (38.5) | 236 (52.7) |  |
ALN status | Â | Â | Â | 0.002 |
Negative | 2415 (64.2) | 2157 (65.1) | 258 (57.6) | Â |
Positive | 1346 (35.8) | 1156 (34.9) | 190 (42.4) | Â |
LVI |  |  |  | <  0.001 |
No | 3477 (92.4) | 3091 (93.3) | 386 (86.2) | Â |
Yes | 284 (7.6) | 222 (6.7) | 62 (13.8) | Â |
ER |  |  |  | <  0.001 |
1–9% | 113 (3.0) | 66 (2.0) | 47 (10.5) |  |
10–49% | 494 (13.1) | 389 (11.7) | 105 (23.4) |  |
≥ 50% | 3154 (83.9) | 2858 (86.3) | 296 (66.1) |  |
PR |  |  |  | <  0.001 |
<  20% | 1671 (44.4) | 1363 (41.1) | 308 (68.8) |  |
≥ 20% | 2090 (55.6) | 1950 (58.9) | 140 (31.3) |  |
Ki-67 |  |  |  | <  0.001 |
<  14% | 1745 (46.4) | 1679 (50.7) | 66 (14.7) |  |
≥ 14% | 2016 (53.6) | 1634 (49.3) | 382 (85.3) |  |