Fig. 7

CDC25A activates the PI3K/Akt signaling pathway. A-B, phosphorylation of PI3K and AKT in ME180 (A) and C33A (B) cells determined by western blot analysis. Data were presented as the mean ± SD from three independent experiments. Data were analyzed by two-way ANOVA followed by Tukey’s multiple comparison test. ***p < 0.01 vs. sh-NC; ##p < 0.01 vs shCDC25A-1 + oe-NC