Fig. 2

Overview of AS profiling and MM-specific exon skipped genes. A Number of AS events and parent genes for each AS event type in 83 MM patients. B UpSet plot of interactions among the seven types of AS events. C KEGG pathway analysis of 103 mutation-associated ES events from 80 genes in MM. The dot size represents the number of enriched genes, and adjusted p values are indicated by the color scale on the side. D Interaction network of 80 ES genes in MM. AA, alternate acceptor; AD, alternate donor; AP, alternate promoter; AT, alternate terminator; ES, exon skip; ME, mutually exclusive exon; RI, retained intron