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Fig. 6 | BMC Cancer

Fig. 6

From: MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2

Fig. 6

Knockdown of ATF2 reverses the growth and migration of HCC cells with over-expression of MARCH6. (a) Immunoblotting analysis of ATF2 in Ctrl, MARCH6 and shMARCH6 + shATF2 Huh7 and HCCLM3 cells. (b and c) Cell proliferation was checked by CCK-8 assay (b) and colony formation was determined (c) in Ctrl, MARCH6 and shMARCH6 + shATF2 Huh7 and HCCLM3 cells. (d) Cell migration was determined by transwell assay in Ctrl, MARCH6 and shMARCH6 + shATF2 Huh7 and HCCLM3 cells. (e) Quantification results of colony formation and cell migration. ** P < 0.01, *** P < 0.001

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