Fig. 5
From: MARCH6 promotes hepatocellular carcinoma development through up-regulation of ATF2
Over-expression of ATF2 restores the growth and migration of MHCC97H cells with down-regulation of MARCH6. (a) Immunoblotting analysis of ATF2 in shCtrl, shMARCH6–1 and shMARCH6–1 + ATF2 MHCC97H cells. (b and c) Cell proliferation was checked by CCK-8 assay (b) and colony formation was determined (c) in shCtrl, shMARCH6–1 and shMARCH6–1 + ATF2 MHCC97H cells. (d) Cell migration was determined by transwell assay in shCtrl, shMARCH6–1 and shMARCH6–1 + ATF2 MHCC97H cells. (e) Quantification results of colony formation and cell migration. * P < 0.05, ** P < 0.01, *** P < 0.001