Table 3 Univariate and multivariate Cox regression analysis in TCGA-LUAD and GSE56044
From: A methylation-based nomogram for predicting survival in patients with lung adenocarcinoma
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | |
TCGA-LUAD cohort | ||||
 Age | ||||
   < = 60/> 60 | 0.96 (0.63–1.47) | 0.852 | 1.19 (0.77–1.85) | 0.437 |
 Sex | ||||
  Male/Female | 0.94 (0.64–1.40) | 0.774 | 0.99 (0.66–1.49) | 0.964 |
 Stage | ||||
  I + II/III + IV | 2.74 (1.82–4.13) | 1.30e-06 | 2.79 (1.85–4.21) | 1.06e-06 |
 Risk score | ||||
  Low/High | 2.22 (1.45–3.42) | 2.77e-04 | 2.29 (1.47–3.57) | 2.36e-04 |
GSE56044 cohort | ||||
 Age | ||||
   < = 60/> 60 | 2.83 (1.26–6.35) | 0.012 | 2.88 (1.26–6.59) | 0.012 |
 Sex | ||||
  Male/Female | 1.10 (0.63–1.93) | 0.737 | 0.79 (0.44–1.43) | 0.438 |
 Risk score | ||||
  Low/High | 2.15 (1.20–3.85) | 0.010 | 2.16 (1.19–3.91) | 0.011 |