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Fig. 5 | BMC Cancer

Fig. 5

From: SERPINE1 associated with remodeling of the tumor microenvironment in colon cancer progression: a novel therapeutic target

Fig. 5

Genes with differential expressions in colorectal cancer patients, and the relationship between SERPINE1 expression and cancer prognosis and staging. B TGFB1 was not significantly expressed in normal and tumor samples, p > 0.05. B SERPINE1 shows differential expression in normal and colon cancer samples, p < 0.05. C Paired analysis of SERPINE1 expression in normal and colon cancer samples, p < 0.05. D Effect of SERPINE1 on the prognosis of colorectal cancer patients. The patients were further divided into two groups based on high or low expression of SERPINE1 according to the median value (assessed using a log-rank test with p = 0.055). E-J The correlation of the expression of SERPINE1 with clinicopathological staging. A Wilcoxon rank-sum or Kruskal-Wallis rank-sum test was utilized

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